Interaction of avian reovirus with chicken lymphoblastoid cell lines

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Methylation of Marek's disease virus DNA in chicken T-lymphoblastoid cell lines.

Methylation of Marek's disease virus serotype 1 (MDV1) DNA in both productively and latently infected cells was examined by restriction endonuclease analyses with the isoschizomeric pair HpaII and MspI. The latent MDV1 DNA in T-lymphoblastoid cell lines established from chicken T-lymphomas was considerably methylated, whereas methylation of the virus DNA sequences was not detected in productive...

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Methylation of Marek's Disease Virus DNA in Chicken T-lymphoblastoid Cell Lines

Methylation of Marek's disease virus serotype 1 (MDV 1) DNA in both productively and latently infected cells was examined by restriction endonuclease analyses with the isoschizomeric pair HpalI and MspI. The latent MDV1 DNA in T-lymphoblastoid cell lines established from chicken T-lymphomas was considerably methylated, whereas methylation of the virus DNA sequences was not detected in productiv...

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Analysis of tumor suppressor gene p53 in chicken lymphoblastoid tumor cell lines and field tumors.

To determine whether there is any abnormalities of the p53 gene in chicken lymphoblastoid tumor cell lines derived from Marek's disease (MD), lymphoid leukosis, reticuloendotheliosis, and field tumors, some portions of p53 cDNA corresponding to core and C-terminal domains (nucleotide positions 277-1104 in the p53 open reading frame (ORF)) were sequenced. Several mutations were identified in bot...

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Proteomics Analysis of the DF-1 Chicken Fibroblasts Infected with Avian Reovirus Strain S1133

BACKGROUND Avian reovirus (ARV) is a member of the Orthoreovirus genus in the Reoviridae family. It is the etiological agent of several diseases, among which viral arthritis and malabsorption syndrome are the most commercially important, causing considerable economic losses in the poultry industry. Although a small but increasing number of reports have characterized some aspects of ARV infectio...

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Chromosomal variation in lymphoblastoid cell lines.

Tens of thousands of lymphoblastoid cell lines (LCLs) have been established by the research community, providing nearly unlimited source material from samples of interest. LCLs are used to address questions in population genomics, mechanisms of disease, and pharmacogenomics. Thus, it is of fundamental importance to define the extent of chromosomal variation in LCLs. We measured variation in gen...

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ژورنال

عنوان ژورنال: Avian Pathology

سال: 1994

ISSN: 0307-9457,1465-3338

DOI: 10.1080/03079459408418996